Nanoflowers Versus Magnetosomes: Comparison Between Two Promising Candidates for Magnetic Hyperthermia Therapy

Promising Therapy Candidates for Liver Fibrosis

Liver fibrosis is a wound-healing process in response to repeated and chronic injury to hepatocytes and/or cholangiocytes. Ongoing hepatocyte apoptosis or necrosis lead to increase in ROS production and decrease in antioxidant activity, which recruits inflammatory cells from the blood and activate hepatic stellate cells (HSCs) changing to myofibroblasts. Injury to cholangiocytes also recruits i...

Enhanced antitumor efficacy of biocompatible magnetosomes for the magnetic hyperthermia treatment of glioblastoma

In this study, biologically synthesized iron oxide nanoparticles, called magnetosomes, are made fully biocompatible by removing potentially toxic organic bacterial residues such as endotoxins at magnetosome mineral core surfaces and by coating such surface with poly-L-lysine, leading to magnetosomes-poly-L-lysine (M-PLL). M-PLL antitumor efficacy is compared with that of chemically synthesized ...

Magnetic Fluid Hyperthermia for Cancer Therapy

The aim of the paper is to show basic ideas of magnetic fluid hyperthermia treatment with regard to power losses which occur during heating with alternating magnetic field. A special attention has been paid to dielectric, hysteresis and relaxation mechanism losses and their contribution to total power losses. A numerical analysis has been done with regard to a simplified female breast phantom a...

Magnetic Gel Composites for Hyperthermia Cancer Therapy

Hyperthermia therapy is a medical treatment based on the exposition of body tissue to slightly higher temperatures than physiological (i.e., between 41 and 46 °C) to damage and kill cancer cells or to make them more susceptible to the effects of radiation and anti-cancer drugs. Among several methods suitable for heating tumor areas, magnetic hyperthermia involves the introduction of magnetic mi...

pegylated superparamagnetic magnetite nanoparticles for magnetic fluid hyperthermia therapy